Versailles, IN—Friday afternoon, at approximately 3:30 pm an Indiana State Police responded to a report on an injury crash involving two vehicles on US 421 south of County Road 1050 South in Ripley County.Troopers arrived to find a 2016 Kia Soul and a 2019 Mitsubishi Mirage in the east ditch of US 421. The preliminary investigation shows that the Kia Soul, driven by Shannon Hubbard, was traveling southbound and was attempting to pass another vehicle. The Mitsubishi Mirage, driven by Henry Finney of Madison, was traveling northbound and could not avoid a collision with the Kia Soul, which was in the northbound lane.Finney was transported by ambulance, to King’s Daughters’ Hospital in Madison where he passed away from his injuries. Hubbard was also transported by ambulance, to King’s Daughters’ Hospital and then transported by lifeline helicopter, to The University of Cincinnati Hospital. Ms. Hubbard was in serious but stable condition.It is believed that both drivers were wearing their seatbelts. Drugs and or alcohol are not believed to be a contributing factor to the crash. Improper passing and traveling at a high rate of speed are believed to be contributing factors to the crash.
Brittle stars are included within a whole range of species, which contribute to knowledge in the medically important area of tissue regeneration. All brittle stars regenerate lose limbs, but the rate at which this occurs is highly variable and species-specific. One of the slowest rates of arm regeneration reported so far is that of the Antarctic Ophionotus victoriae. Additionally, O. victoriae also has an unusual delay in the onset of regeneration of about 5 months. Both processes are of interest for the areas of regeneration biology and adaptation to cold environments. One method of understanding the details of regeneration events in brittle stars is to characterise the genes involved. In the largest transcriptome study of any ophiuroid to date, we describe the results of mRNA pyrosequencing from pooled samples of regenerating arms of O. victoriae. The sequencing reads resulted in 18,000 assembled contiguous sequences of which 19% were putatively annotated by blast sequence similarity searching. We focus on the identification of major gene families and pathways with potential relevance to the regenerative processes including the Wnt/β-catenin pathway, Hox genes, the SOX gene family and the TGF beta signalling pathways. These data significantly increase the amount of ophiuroid sequences publicly available and provide candidate transcripts for the further investigation of the unusual regenerative process in this Antarctic ophiuroid.