Republic of Ireland have been boosted by the return of striker Shane Long to training ahead of their 2018 FIFA World Cup qualifiers against Moldova and Wales.The 30-year old Southampton striker missed Monday and Tuesday’s sessions due to a leg injury but the former Reading and West Brom player returned to training on Wednesday and is now expected to be available for Friday’s must-win game against Moldova.Injury-doubts James McCarthy (knee) and Harry Arter (calf) trained on Wednesday but they are unlikely to start against Moldova.One man that’s expected to miss out on the two qualifiers altogether is Burnley forward Jonathan Walters, who is absent because of a knee injury. Club teammate Robbie Brady is suspended for the first game against Moldova alongside West Brom winger James McClean.Republic of Ireland have to win at home against Moldova and then beat Wales to have a chance of making the 2018 FIFA World Cup play-offs in the European section.RelatedBig Blow! Striker Out Of Crucial Derby Clash With WalesOctober 9, 2017In “FIFA”McAuley Returns To NI Squad Ahead Of World Cup QualifiersSeptember 26, 2017In “FIFA”2018 FIFA World Cup Qualifying Wrap (UEFA): Serbia, Iceland Secure Spots; Wales Suffer HeartbreakOctober 10, 2017In “FIFA”
Brittle stars are included within a whole range of species, which contribute to knowledge in the medically important area of tissue regeneration. All brittle stars regenerate lose limbs, but the rate at which this occurs is highly variable and species-specific. One of the slowest rates of arm regeneration reported so far is that of the Antarctic Ophionotus victoriae. Additionally, O. victoriae also has an unusual delay in the onset of regeneration of about 5 months. Both processes are of interest for the areas of regeneration biology and adaptation to cold environments. One method of understanding the details of regeneration events in brittle stars is to characterise the genes involved. In the largest transcriptome study of any ophiuroid to date, we describe the results of mRNA pyrosequencing from pooled samples of regenerating arms of O. victoriae. The sequencing reads resulted in 18,000 assembled contiguous sequences of which 19% were putatively annotated by blast sequence similarity searching. We focus on the identification of major gene families and pathways with potential relevance to the regenerative processes including the Wnt/β-catenin pathway, Hox genes, the SOX gene family and the TGF beta signalling pathways. These data significantly increase the amount of ophiuroid sequences publicly available and provide candidate transcripts for the further investigation of the unusual regenerative process in this Antarctic ophiuroid.